Subcutaneous Injection

Introduction To Subcutaneous Injection

Subcutaneous injection is a method of administering biopharmaceutical products through the subcutaneous tissue, for example measles vaccine, mumps vaccine , insulin, monoclonal antibodies, interferon, heparin, and hematopoietic growth factors. Subcutaneous injection can also be used to provide local anesthesia as well as drugs in palliative care, such as morphine and fentany

In the subcutaneous injection procedure, a liquid biopharmaceutical product is injected into the fat layer of the subcutaneous tissue. Because this tissue has few blood vessels, the drug given will be absorbed slowly and gradually. This allows drugs that are administered subcutaneously into the circulation at continuously low doses, such as insulin .[2]

Subcutaneous injection has several advantages over other injection methods, namely no special skills are required for the procedure, the injection site can move for multiple doses of drugs, minimal pain effects, and a lower risk of infection than intravenous or intramuscular injection. [1]

Although it has many advantages, subcutaneous injection also has some disadvantages, especially in repeated injections. Subcutaneous injection has the potential to produce different levels of drug absorption at each injection time in the same patient. In addition, with repeated injections, there is a risk of local discomfort, pain, and skin disorders at the injection site.[2]

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